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However, it can cause kidney damage, leading to impaired renal function, increased BUN and SCr levels, reduced glomerular filtration, and histopathological changes like mesangial cell hypercellularity, glomerular atrophy, tubular necrosis, degeneration, and vacuolization 7,8

Before each evaluation, the mice were examined carefully for perineal infection, wounds in the hindlimbs, tail and foot

Lyophilization improves stability during storage and allows reconstitution before use in settings where a clinician has recommended it

It is a metabolic optimizer